Section Contents: -- Preface -- Acknowledgments -- Part I: The Challenge of Biodefense -- Part II: Organizations that Conduct Biosurveillance and the Data they Collect -- Part III: Analysis -- Part IV. Other Sources of Surveillance Data -- Part V: Decision Making -- Part VI: Building Biosurveillance Systems -- Epilogue: The Future of Biosurveillance.

pt. I. The challenge of biosurveillance. Introduction / Michael M. Wagner -- Outbreaks and investigations / Virginia Dato, Richard Shephard, and Michael M. Wagner -- Case detection, outbreak detection, and outbreak characterization / Michael M. Wagner, Louise S. Gresham, and Virginia Dato -- Functional requirements for biosurveillance / Michael M. Wagner, Loren Shaffer, and Richard Shephard -- pt. II. Organizations that conduct biosurveillance and the data they collect. Governmental public health / Rita Velikina, Virginia Dato, and Michael M. Wagner -- The healthcare system / Michael M. Wagner, William R. Hogan, and Ron M. Aryel -- Animal health / Richard Shephard, Ron M. Aryel, and Loren Shaffer -- Laboratories / Charles Brokopp [and others] -- Water suppliers / Jason R.E. Shepard [and others] -- Food and pharmaceutical industries / Ron M. Aryel and T.V. (Sunil) Anklekar -- Coroners and medical examiners / Ron M. Aryel and Michael M. Wagner -- Other organizations that conduct biosurveillance / Michael M. Wagner [and others] -- pt. III. Data analysis. Case detection algorithms / Fu-Chiang Tsui [and others] -- Classical time-series methods for biosurveillance / Weng-Keen Wong and Andrew W. Moore.

Combining multiple signals for biosurveillance / Andrew W. Moore [and others] -- Methods for detecting spatial and spatio-temporal clusters / Daniel B. Neill and Andrew W. Moore -- Natural language processing for biosurveillance / Wendy W. Chapman -- Bayesian methods for diagnosing outbreaks / Gregory F. Cooper [and others] -- Atmospheric dispersion modeling in biosurveillance / William R. Hogan -- Methods for algorithm evaluation / Michael M. Wagner and Garrick Wallstrom -- pt. IV. Newer types of surveillance data. Methods for evaluating surveillance data / Michael M. Wagner -- Sales of over-the-counter healthcare products / William R. Hogan and Michael M. Wagner -- Chief complaints and ICD codes / Michael M. Wagner [and others] -- Absenteeism / Leslie Lenert [and others] -- Emergency call centers / Ron M. Aryel and Michael M. Wagner.

The internet as sentinel / Michael M. Wagner, Heather A. Johnson, and Virginia Dato -- Physiologic and space-based sensors / Ron M. Aryel -- Data NOS (not otherwise specified) / Michael M. Wagner and Murray Campbell -- pt. V. Decision making. Decision analysis / Agnieszka Onisko, Garrick Wallstrom, and Michael M. Wagner -- Probabilistic interpretation of surveillance data / Garrick Wallstrom, Michael M. Wagner, and Agnieska [sic] Onisko -- Economic studies in biosurveillance / Bruce Y. Lee [and others] -- pt. VI. Building and field testing biosurveillance systems. Information technology standards in biosurveillance / William R. Hogan and Michael M. Wagner -- Architecture / Jeremy Espino and Michael M. Wagner -- Advancing organizational integration: negotiation, data use agreements, law and ethics / M. Cleat Szczepaniak [and others] -- Other design and implementation issues / Steve DeFrancesco, Kevin Hutchison, and Michael M. Wagner -- Project management / Neil Jacobson, Sherry Daswani, and Per H. Gesteland -- Methods for field testing of biosurveillance systems / Michael M. Wagner.