Endocrine manifestations of systemic autoimmune diseases / edited by Sara E. Walker and Luis J. Jara.

ISBN:

9780444531728

9780080570303

Title:

Endocrine manifestations of systemic autoimmune diseases / edited by Sara E. Walker and Luis J. Jara.

Author:

Walker, Sara E.

Publication Information:

Amsterdam : Elsevier Science, 2008.

Physical Description:

1 online resource (xvii, 330 pages, [3] pages of plates) : illustrations (some color), 1 map.

Series:

Handbook of systemic autoimmune diseases, v. 9

Contents:

PATHOPHYSIOLOGY: -- Neuroendocrine Immune Control Mechanisms and their influence on autoimmune disease; -- Sex Steroids, the immune system and autoimmune disease; -- Autoimmune disease and influence of sex hormones in experimental animals; -- Genetics of Autoimmune Endocrine Diseases; -- CLINICAL: -- Pituitary; -- Thyroid Dysfunction in Autoimmune Diseases; -- Adrenal Dysfunction and Autoimmune Disease; -- Endometriosis; Genetic abnormalities, hormones and autoimmune diseases; Polyglandular Autoimmune Endocrine Disease; -- Diabetes Type 1; -- Autoantibodies and Infertility in Autoimmune Diseases; -- Systemic Lupus Erythematosus and Endocrine Disorders; -- Pregnancy, neuroendocrine immune system and autoimmune diseases; -- HORMONAL MODULATION IN THE THERAPY OF AUTOIMMUNE DISEASES: -- Ovarian Function and its preservation in Autoimmune Diseases; Corticosteroids; -- Prolactin; -- DHEA; -- Adenosine agonists; -- NOVEL THERAPIES: -- New Treatments for Graves? Disease; -- Anti-TNF therapy -- modulation of hormone axes; -- Islet-cell transplantation; -- "Immune Intervention in Type 1 Diabetes: Realities of Today and Hopes for Tomorrow."

Local Note:

eBooks on EBSCOhost

Subject Term:

Endocrine manifestations of general diseases.

Autoimmune diseases -- Endocrine aspects.

Added Author:

Walker, Sara E.

Jara, Luis J., 1948-

Format:

Electronic Resources

Electronic Access:

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Publication Date:

2008

Publication Information:

Amsterdam : Elsevier Science, 2008.

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Shelf Number	Material Type	Copy	Shelf Location	Status
616.4 22	1:E-BOOK	1	1:ONLINE	Searching... Unknown

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Summary

This book is one of the first to evaluate the role of Steroids in autoimmune rheumatic diseases from the basic mechanisms to the clinical involvements and focuses on the importance of steroidal hormones in the pathogenesis and therapeutic management of the autoimmune rheumatic diseases. In particular, the chapters analyze the mechanisms of action and the involvement of adrenal steroids (glucocorticoids) in the neuroendocrine immune system, including effects on the elderly. The perturbations of the HPA axis as a source of altered steroidal synthesis will be discussed and related to some interesting pathological conditions that commonly complicate the autoimmune rheumatic diseases such as psychosis or fibromyalgia. Concerning the role of gonadal steroids (sex hormones), several chapters will discuss clinical and epidemiological evidences of their role, as well as their effects as risk factors in autoimmune rheumatic diseases, including a section on pediatrics.

Author Notes

DRG Publishing is a leader in craft-book publications and includes the imprints American School of Needlework, Annie's Attic, House of White Birches, and the Needlecraft Shop.

Silvia Capellino and Rainer H. StraubMaurizio Cutolo and Silvia Capellino and Rainer H. StraubElena Peeva and Gisele Zandman-Goddard and Yehuda ShoenfeldAnnamaria De Bellis and Antonio Bizzarro and Antonio BellastellaJennifer M. BarkerYaron TomerAlejandro Ruiz-Arguelles and Mario Garcia-CarrascoAnnamaria Colao and Lidice Bradao Tavares and Rosario Pivonello and Gaetano Lombardi and Diego FeroneManuel Ramos-Casals and Pilar Brito-Zeron and Gerard Espinosa and Ricard CerveraSandra G. Pasoto and Mauricio S. Abrao and Sergio Podgaec and Eloisa BonfaPaul E. Belchetz and Carol E. Chu and Ramzi AjjanCorrado Betterle and Fabio PresottoImad Uthman and Munther KhamashtaHoward J.A. Carp and Asher Ornoy and Yehuda ShoenfeldSara Cortes and Ana Jeronimo and David IsenbergLuis J. Jara and Gabriela Medina and Carmen Navarro and Miguel A. Saavedra and Francisco Blanco-Favela and Luis R. EspinozaR. Hal ScofieldJuan-Manuel Anaya and Rodrigo Corena and Veronica AbadSangeeta D. Sule and Michelle PetriJohannes W.J. Bijlsma and Frank Buttgereit and Maurizio Cutolo and Jose Antonio P. da SilvaSara E. WalkerGabriela Schiechl and Rainer H. StraubRoberto Caporali and Carlomaurizio MontecuccoMiguel A. Gonzalez-Gay and Ricardo BlancoChristian Toso and A.M. James ShapiroYoav Arnson and Howard Amital and Yehuda ShoenfeldFabiola Atzeni and Piercarlo Sarzi-Puttini and Maurizio Cutolo and Rainer H. Straub

Preface	p. v
Series Editor	p. vii
Volume Editors	p. ix
List of Contributors	p. xi
I Pathophysiology
Neuroendocrine Immune Control Mechanisms and their Influence on Autoimmune Disease	p. 3
Sex Hormones, the Immune System and Autoimmune Diseases	p. 13
Gender Bias in Murine Lupus	p. 21
Role of Prolactin in Autoimmune Diseases	p. 29
The Pathogenesis of Type 1 Diabetes	p. 45
The Genetics of Autoimmune Thyroid Diseases	p. 61
Thyroid Dysfunction and the Immune System	p. 75
II Clinical Aspects
Autoimmunity and the Pituitary Gland	p. 83
Adrenal Involvement in Systemic Autoimmune Diseases	p. 95
Endometriosis and Autoimmunity	p. 103
Autoimmunity in Turner's, Down's, and Klinefelter's Syndromes	p. 113
Autoimmune Polyendocrine Syndromes (APS) or Multiple Autoimmune Syndromes (MAS)	p. 135
Endocrine Manifestations of the Antiphospholipid Syndrome	p. 149
Autoantibodies and Infertility in Autoimmune Diseases	p. 157
Systemic Lupus Erythematosus and Endocrine Disorders	p. 173
Pregnancy, Hormones, and Autoimmune Rheumatic Diseases	p. 185
Autoimmune Hypothyroidism and Hyperthyroidism in Systemic Autoimmune Disease	p. 199
Type 1 Diabetes Mellitus at the Crossroad of Polyautoimmunity	p. 211
III Hormonal Modulation in the Therapy of Autoimmune Diseases
Estrogen in Systemic Lupus Erythematosus: Lessons from the SELENA Study	p. 223
Hormonal Modulation of Autoimmune Diseases: Glucocorticoids	p. 229
Estrogen and Prolactin: Contributions to Autoimmunity in Murine Models of Systemic Lupus Erythematosus	p. 241
Dehydroepiandrosterone	p. 249
Glucocorticoid Therapy for Polymyalgia Rheumatica	p. 257
Danazol Therapy	p. 265
IV Novel Therapies
Islet Transplantation for the Treatment of Type I Diabetes	p. 275
The Immunoendocrine Role of Vitamin D in Autoimmunity	p. 293
Modulation of Hormone Axes by Anti-TNF Therapy	p. 301
Subject Index	p. 309
Colour Plate Section

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Summary

Author Notes

Table of Contents